Fosamax (generic: alendronate sodium) is a bisphosphonate drug manufactured by Merck; it gained FDA approval on September 29, 1995. It generated three billion dollars of revenue for Merck in 2006. In 2004, the FDA and Merck, as well as the manufacturers of other bisphosphonates, updated the labels to warn about osteonecrosis of the jaw.
Drugs in the Bisphosphonate class are used to prevent bone loss. They are prescribed to treat osteoporosis, advanced cancers that have metastasized to the bone, and Paget's disease. Many drugs in the class are high dose and are administered intravenously, but Fosamax is typically prescribed in the oral version. It was originally thought that ONJ only developed in cancer patients taking the intravenous bisphosphonates (Aredia, Zometa and Bonefos), but now there are widespread reports of the condition in those taking oral Fosamax and oral Fosamax Plus D. To explore your legal rights and to receive a free consultation about your potential Fosamax case, please call 1-866-50-RIGHTS (1-866-507-4448).
In the January 15, 2008 Journal of Rheumatology issue, a study was published on oral bisphosphonate use and osteonecrosis. It examined 87,837 cardiovascular elderly Quebec patients and used health database medical records. The study found an elevated risk of osteonecrosis among oral bisphosphonate users. Fosamax (alendronate) was one of the drugs showing an elevated osteonecrosis risk among these patients.
Many people believe that Fosamax was over-prescribed to many postmenopausal women and that as a result, ONJ cases are on the rise. Please fill out our short and simple online form at the right or call 1-866-50-RIGHTS (1-866-507-4448) to speak to someone directly about your case. Fosamax users have valuable legal rights.
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